Lycopene and Its Potential Role in Prostate Cancer Prevention

A Trion, FH Schröder, WM van Weerden - Lycopene, 2019 - taylorfrancis.com
… In this study, no benefit of flutamide as a chemopreventive … -blind, placebo-controlled
chemoprevention study and aims to … Flutamide in men with prostatic intraepithelial neoplasia: a …

Drug-induced gynecomastia: A systematic review and meta-analysis of randomized clinical trials

A Trinchieri, G Perletti, V Magri… - ARCHIVIO …, 2021 - irinsubria.uninsubria.it
… There was an increased odds of gynecomastia in men … No placebo-controlled trials focusing
on the risk of … non-steroidal like flutamide, have also been used for the treatment of prostate

Estrogen and androgen blockade for advanced prostate cancer in the era of precision medicine

T Fujimura, K Takayama, S Takahashi… - The Road from …, 2019 - taylorfrancis.com
Chemoprevention, prostate-specific antigen (PSA) … study used toremifene at a dose of 20
to 60 mg to prevent PC incidence in men with high-grade prostatic intraepithelial neoplasia (…

The possibility of preventive and therapeutic use of green tea catechins in prostate cancer

VS Rogovskii, SV Popov, NV Sturov… - Anti-Cancer Agents …, 2019 - ingentaconnect.com
… the efficacy of chemopreventative agents Dutasteride, Flutamide, … with high-grade prostatic
intraepithelial neoplasia (HGPIN): A … A double-blind, placebo-controlled randomised trial

[HTML][HTML] Androgen receptor and soy isoflavones in prostate cancer

MK Sivoňová, P Kaplán… - Molecular and …, 2019 - spandidos-publications.com
… The protective role of daidzein on flutamide-induced … of double-blind placebo-controlled
randomized clinical trials (15,115–… from prostatic intraepithelial neoplasia to high grade prostatic

[HTML][HTML] Dietary factors and prostate cancer development, progression, and reduction

M Oczkowski, K Dziendzikowska… - Nutrients, 2021 - mdpi.com
… which prostatic intra-epithelial neoplasia develops [28]. … meta-analysis of randomized,
placebo-controlled trials concerning the … receptor, synergy with flutamide, and the enhancement of …

Toward improving androgen receptor-targeted therapies in male-dominant hepatocellular carcinoma

H Zhang, K Spencer, SK Burley, XFS Zheng - Drug discovery today, 2021 - Elsevier
… Given that HCC is a male-dominant malignancy in which AR … and flutamide have been
tested in human clinical trials. … Similarly, in another human clinical trial with male patients …

Therapeutic applications of the prostate cancer epigenome

JM Cosgrave, AS Perry - Epigenetic Cancer Therapy, 2023 - Elsevier
… , raising the possibility of chemoprevention via control of the … high-grade prostatic intraepithelial
neoplastic (HGPIN) lesions, … in men following complete androgen blockade and flutamide

[HTML][HTML] Organoids Increase the Predictive Value of in vitro Cancer Chemoprevention Studies for in vivo Outcome

RN Njoroge, RJ Vatapalli, SA Abdulkadir - Frontiers in Oncology, 2019 - frontiersin.org
men will be diagnosed with PCa and 29,430 men will die from the disease (1). For men
with … Focal loss of ECM and integrin attachment in prostatic intraepithelial neoplasia lesions …

[HTML][HTML] Resistance to antiandrogens in prostate cancer: is it inevitable, intrinsic or induced?

NJ Maitland - Cancers, 2021 - mdpi.com
… earlier steroidal anti-androgen flutamide, is more commonly … -initiating population of prostate
epithelial cells but upregulated … the FDA in a chemoprevention role for prostate cancer, and …